In the upcoming weeks, we are proud to announce the release of our latest application note regarding concentration dependence in protein viscosity. In this app note, Dr. Stacey Elliott gathered viscosity data for Bovine Gamma Globulin (BgG) formulations over the full concentration range, including therapeutic levels ≥ 100 mg/mL, using the VROC®Initium. The solution buffer included sucrose which is a common additive to enhance stabilization during freeze-drying and storage. Relative viscosity versus concentration curves were fit with the Ross-Minton equation which is a frequently used analysis tool for protein formulations.
To view application note, click below!
According to a GEN – genetic engineering & biotechnology article, researchers found that the consumption of coffee stimulates the complex network of neurotransmitters, also known as the endocannabinoid system (ECS), much like that of cannabis. ECS consists of a biological structure composed of endocannabinoids, which are essentially the "small molecules that activate the cannabinoid receptors" (Jikomes). ECS is a system that is necessary in maintaining homeostasis on a cellular level. Furthermore, ECS is also responsible as it acts as a regulator for stress response, appetite, addiction, energy, and much more (GEN).
Measuring viscosity dates back to as early as the 19th century. French physicist Jean Poiseuille discovered the concept of measuring viscosity by formulating the "mathematical expression for the flow rate for the laminar flow of fluids in circular tubes." Later on, this formulation was discovered by a German hydraulic engineer Gotthilf Hagen, which came to be known as the Hagen-Poiseuille equation (Britannica). Early measurements of viscosity focused primarily on the flow of blood. Measurements were conducted using the hemodynamometer that incorporated narrow tubes & glass capillaries in effort to measure the pressures in the arteries of horses and dogs (Sutera).
Recently we received our first order from Saudi Arabia. The order is from the leading university in Saudi Arabia and they order an m-VROC® with multiple chips.
*Lu's Corner is a new concept hosted by our Technical Specialist, Lu Lu. Lu has been a Technical Specialist with RheoSense for over 2 years. Through meticulous customer relationship development and continuous exploration of new applications, Lu has been able to provide a level of outstanding customer service and support.
What do we talk about when we talk about viscosity? A series stories of viscosity in life.
Story One - Cosmos and Cosmetics
Did you know that even a deadweight machine that is capable of applying 4,448,222 Newtons or 1 million pounds of force?
Science is the study of the world using collected knowledge, observation, and experimentation. Those in the sciences are generally known for being quite serious, dare I say, dull. However, that is not always the chase. Take for example Albert Einstein, unquestionably one of the most brilliant minds to ever inhabit the earth, but also a wit and sense of humor maybe equally as impressive. In this blog, I’d like to share some funny Einstein quotes as well as quotes from other brilliant minds. Enjoy!
According to a recent discovery, a frog is able to change the viscosity of its saliva in order to catch its prey. When extending its tongue out at the prey, the viscosity of the frog's saliva decreases. Once the prey is on the frog's tongue being drawn closer to the frog, the frog's saliva thickens up far more viscous than honey.Read our application notes on kinetic studies!