<img height="1" width="1" style="display:none;" alt="" src="https://dc.ads.linkedin.com/collect/?pid=510762&amp;fmt=gif">

Latest Release & Upcoming Events

In the upcoming weeks, we are proud to announce the release of our latest application note regarding concentration dependence in protein viscosity. In this app note, Dr. Stacey Elliott gathered viscosity data for Bovine Gamma Globulin (BgG) formulations over the full concentration range, including therapeutic levels ≥ 100 mg/mL, using the VROC®Initium. The solution buffer included sucrose which is a common additive to enhance stabilization during freeze-drying and storage. Relative viscosity versus concentration curves were fit with the Ross-Minton equation which is a frequently used analysis tool for protein formulations.

To view application note, click below!

DOWNLOAD APPLICATION NOTE

In Viscosity Measurements, VROC Technology, Rheometer, General Information, Proteins, Viscometer, Small Sample Viscometer, RheoSense News, Announcement, viscosity, Fun with Viscosity, Protein Solutions, bovine gamma globulin, shear rate sweep

Viscosity Reduction in Protein Solutions

In case you haven't seen it yet, we released a new app note last week regarding viscosity reduction in protein solutions. In this application note, Dr. Elliott discusses the idea that the viscosity of a protein solution depends on the nature of the individual and protein-protein interaction (PPI). Both of the individual characteristics, such as size and shape, as well as the pair interactions can be influenced by components in the buffer formulation. As a result, it is often desirable to reduce viscosity values so that formulations are suitable for a particular application or process (ie: injection).

In viscosity, Protein Solutions, bovine gamma globulin, shear rate sweep, Amino acids, Viscosity Reduction