We hope that everyone's last week of march is nothing short of positivity and growth. It has been an extremely busy month (& that's not a complaint) for most of us! And of course increasing productivity often yields the best results, right?
My name is Ecko Chen, and I am the Mechanical Engineer here at RheoSense. My coworker Brandon has introduced a consumable list for the VROC® Initium maintenance in the previous post. I am going to expand a little on one of the most common consumable replacements --- The septa.
My name is Brandon Bell and I am the Process Engineer here at RheoSense. I am responsible for the production of the VROC® Initium product line and I wanted to take a few minutes to provide you a few tips and tricks that I have picked up to help you get the most out of your instrument.
We frequently get the question, "how do I know that my equipment is working, or that these tests are accurate?" The best way to determine this and be sure of your results is to run a system suitability test.
In the upcoming weeks, we are proud to announce the release of our latest application note regarding concentration dependence in protein viscosity. In this app note, Dr. Stacey Elliott gathered viscosity data for Bovine Gamma Globulin (BgG) formulations over the full concentration range, including therapeutic levels ≥ 100 mg/mL, using the VROC®Initium. The solution buffer included sucrose which is a common additive to enhance stabilization during freeze-drying and storage. Relative viscosity versus concentration curves were fit with the Ross-Minton equation which is a frequently used analysis tool for protein formulations.
To view application note, click below!
Measuring viscosity dates back to as early as the 19th century. French physicist Jean Poiseuille discovered the concept of measuring viscosity by formulating the "mathematical expression for the flow rate for the laminar flow of fluids in circular tubes." Later on, this formulation was discovered by a German hydraulic engineer Gotthilf Hagen, which came to be known as the Hagen-Poiseuille equation (Britannica). Early measurements of viscosity focused primarily on the flow of blood. Measurements were conducted using the hemodynamometer that incorporated narrow tubes & glass capillaries in effort to measure the pressures in the arteries of horses and dogs (Sutera).
RheoSense is will be exhibiting at the 2016 BioProcessing Summit from August 15 to August 19. Visit us at Booth #101 to meet our specialists and see the newautomatic, high throughput viscometer, VROC® initium!
RheoSense is will be exhibiting at the 2016 Society for Laboratory Automation and Screening (SLAS) Conference from January 23rd to the January 27th. Visit us at Booth #601 to meet our specialists and see the new automatic, high throughput viscometer, VROC® initium!