Injectability is a common screening criteria when determining the candidacy of protein therapeutics. Often times, the candidate protein therapeutics are scrutinized if the viscosity is higher than the pre-set threshold where the cut off viscosity ranges from 20 to 40 mPa-s depending on the delivery device. However, this type of generalization without specifying the shear rate could potentially lead to a false negative determination of an otherwise excellent therapeutic resulting in significant financial loss and time during development.
Measuring small incremental changes in low viscosity samples is challenging. And when we mention low viscosity samples, we mean low (measuring as low as 0.4 or around 1 cP). Our microfluidics based automatic viscometer facilitates this process using a fraction of the volume required for more traditional methods.
Join our webinar where we will present data and analysis to illustrate the following.
A lot of my customers have admitted to measuring viscosity at a shear rate of 1,000 1/s when it comes to formulating various types of drugs including injectables. However, from our recent in-depth analysis of various salt concentrations added to proteins, our results further confirmed why you are not getting your full spectrum when it comes to measuring your proteins at just one and a low shear rate of 1,000 1/s.
On August 5, 2019 at 10:00 am PST at Oaksterdam University in Oakland California, our Technical Specialists will be giving a talk on cannabis extracts and where viscosity is important.
Sign up for the event here: https://learn.oaksterdamuniversity.com/cannabis-extraction-operations-seminar/
We recently hosted a webinar where we went into details on viscosity measurements used as a guide when it comes to formulation development and the recording is now ready!
We will be exhibiting at the upcoming BioProcessing Summit Conference taking place at the Seaport World Trade Center in Boston, Massachusetts.
Recently, one of my customers brought up a concern that she had seen through other lab instrumentation during her experience in the lab. She asked how we deal with the particular evaporation effects of protein or other samples, especially when it comes to our VROC initium which handles 40 samples or up to 96 samples. So we put it to the test.
Outside of our current pictures or knowledge of the universe lies plasma which is comprised of electrons and nuclei. Due to the lack of knowledge, it is quite difficult to review the behavior of the plasma. However, scientists are aware that the plasma behavior indicates low viscosity behavior resulting in irregularities. Separately, depending on the positioning of the plasma along the magnetic field lines, speculation is that viscosity could vary.
Do you work in the biopharm or biotech industry? Do you work with proteins and currently measure protein viscosity or has the topic come up during conversations and meetings? Many of our customers reference our company not just for viscometers but for the various application notes that we have. We have a wide variety of application notes ranging from ink, oil, cosmetics, and all types of applications which you can explore here: