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You may have followed many of our injectability application notes and webinar sessions where we began to explain the concept of calculating injection rates. Our next webinar this coming month on November 20, 2019 at 11:00 am PST will actually be a hands-on live workshop where we will start from scratch on how to approach the calculations to injection rate, figuring out which shear rates to run, and ultimately designing your experiments with the real application in mind.
Measuring viscosity at a single and arbitrary shear rate provides limited information which can be difficult to interpret. A much more thorough understanding of a formulation is obtained by measuring the shear rate dependence. In addition to the practical relevance of predicting the behavior during application or processing, the details of a non-Newtonian response reflect the molecular interactions and resulting microstructure at therapeutic levels. Even protein solutions at moderate concentrations can exhibit a Newtonian plateau followed by a shear thinning region illustrating the importance of non-hydrodynamic forces and degree of structure formation.
Intrinsic viscosity has been a parameter commonly used in the waste and recycle process. Based on a recently published article on Engineer Live, about 46% of waste in the oceans have been directed to fishing nets. On top of recycle programs and efforts to reduce the amount of waste, a company called Plastix A/S uses methods to reduce viscosity of the fishing nets which are mainly polyethylene (HDPE). Using compatible polymers, industry developers have been reviewing the potential to use various polymer dynamics to deter a continuous use of material into a method of cycled reuse.
Trilogy Bio, Inc. is hosting a 2019 Emeryville tradeshow where RheoSense, Inc. Technical Specialists will be on-site to help answer any questions.
Our new application note is ready for download! As a sequel to our "Can Your Proteins Take the Heat," we have come out with part 2 where we go into further research on how varying pH with dilute proteins at varied temperatures can impact the viscosity. From there, viscosity values can be used to derive the protein to protein interaction and also the melting transition or protein denaturation process.
It took quite some time but we are proud to announce our customer portal! Through this portal, you can now access software, full manuals, and additional service notes. You will also get a chance to sign up for exclusive product updates, technical application notes, and exclusive scientific data that we are obtaining from our labs!
